Thursday, February 21, 2008

rechargable brain...?

As we speak there are laboratories and teams working all over the world on systems that will directly connect circuits from silicone chips to our neural circuits, and it may come as a surprise to you that some are just about ready for commercial launch, at least according to a new report from the World Technology Evaluation Center and announced by a news release of the University of Southern California (USC). Some of the conclusions of this report about brain-computer interfaces (BCIs) are quite surprising at least to a jaded mind like mine.
For example, North America researchers focus almost exclusively on invasive BCIs while European and Asian labs tend to examine non-invasive BCI systems. (hmm...). If you don’t have enough time to read the 234-page report between late night exams crams and latte dates at starbucks, not to worry, here is a cheat note version of the more exciting excerpts from the weighty tome:)

And for those of you research oriented, here's the link to this report, “International Assessment of Research and Development in Brain-Computer Interfaces” (PDF format, 234 pages, 5.90 MB), available online on the World Technology Evaluation Center (WTEC) website. Basically the report contains the three noteworthy perspectives on Brain-Computer Interface (BCI) work worldwide:
As you can imagine R&D on Brain-Comp Interface, or BRaCO (an acronym that I much prefer over BCI which always sounded vaguely like a telecom company or maybe it just reminds me of that ill fated MCI:) research is extensive and rapidly growing, as is exponential expansion in the interaction between multiple key scientific areas, including biomedical engineering, neuroscience, gen-comp circuitry mapping, materials science and nanotechnology, not to mention neurphysiology and neurosurgery.
BRaCO research is rapidly approaching Generation One clinical trials of invasive BRaCO technologies and widely commercialized use of noninvasive, electroencephalography (EEG) BRaCo devices. The panel predicts that BRaCOs soon will markedly influence the emerging biomedical tech industry (think robotics here), enabling prototype version of the 'Terminator' and inevitably of course progressing to non-medical arenas of commerce as well, arguably in weapons industry, gaming, transport.

Frankly the idea of a functional let alone benevolent T1 robot sounds overly optimistic to me at this point, given that the focus of BRaCO research throughout the world is decidedly uneven, with invasive BRaCOs almost exclusively centered in United States (hmm..military budget?), noninvasive BRaCO systems evolving primarily from European and Asian efforts. BRaCO research in pacific rim nations, particularly China surprise surprise, is accelerating, with advanced algorithm development for EEG-based systems currently a pivotal linchpin of China’s BRaCO program. Future BCI research in China is clearly developing toward invasive Brain-Computer Interface systems, so BCI researchers in the US will soon have a strong competitor, thus raising the specter of a new 'BRaCO arms race' between the two superpowers, and no we definitely are not talking about russians here:((

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Wednesday, January 30, 2008

:(

Russia's most famous bodyguard, 29 year-old former model Anna Loginova, has been in killed in a carjacking. The glamorous 29-year-old died from head injuries after clinging on to the door handle of her Porche Cayenne and being dragged along the street at high speed as the car screeched away.

Loginova ran an agency for female bodyguards, some trained by the ex-KGB, to give discreet protection to Moscow's billionaires and their wives and mistresses...
"A normal man gets sick and tired of male bodyguards around him all the time," she said.
Her most famous client was rumored to be Kosta Tszyu, the Russian-Australian welterweight boxing champ.

Pravda reports that, on Sunday night, Loginova "arrived on her prestigious car to Moscow’s Novomarinskaya Street to purchase a kitten from someone. The next moment a Russian-made car stopped near the silvery Porsche. A young dark-haired man stepped out of the car and ran towards Anna’s vehicle."

The man pulled the door open, grabbed the woman and dragged her our of the car. Afterwards, he quickly got into her Porsche Cayenne and shut the door. Everything happened in an instant. However, the young woman did not intend to give up without a fight. She got up onto her feet and gripped the handle on the door of her car. The woman did not let it go even when the car tore away.

The hijacker dragged the Porsche owner several meters before she released her hands. The woman hit her head on the asphalt road and died of a serious cranial injury. It turned out later that it was not the first incident, when hijackers attempted to steal Anna Loginova’s car. In December of 2007, the model said in an interview with Maxim magazine that she had already been a victim of such street attacks.

“I stepped out of my car and closed the door when I suddenly saw a young man near me. He grabbed me by the arm in which I was holding the car keys. By reflex, I used a Jiu-Jitsu technique. I twisted his arm and hit him on the face with my elbow. The guy obviously was not expecting such a reaction. He fell down on the rear windshield, which gave me enough time to grab my gun. He immediately jumped into his Honda and drove away,” the model said in an interview.

The second time around, she was not so lucky :(

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Sunday, January 20, 2008

another sign winter has arrived...



Sigh.. so you know we would love to do anything for a good cause, but this is a tad little too risqué even for us brainwash gals :( Thankfully not everyone feels the same way, as witness this ringing endorsement from a motivated Swim Team member; (granted it does benefit the Swim Team..but still!~)


"..the rousing highlight of the winter: Most definitely stripping on the street to help raise money for the McGill Varsity Swim team. We were all standing on the street in their swimsuits freezing in the streets (temperature? -14degrees! Wow!) They were so stoked when we stripped off our clothes, (all except undies) and started collecting money. People on the street didn't know what to think but they gave us money. Everyone was shivering but laughing."

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Saturday, October 20, 2007

buying porn with McGill


Headline:

McGill seeks to protect its name, reassesses use of 'McGill' in student-run organizations


Dear Editor;

Boy, was I ever pissed off when I opened the mail! I did my undergrad at McGill, so I’m also a McGill alumni, which means I get McGill stuff in the mail. I was just offered the McGill Platinum card: up to a $100,000 limit and I get an official McGill University bag ($34.95 value!!)

Not only am I angry that my personal information was sold to MasterCard, but isn’t there this big licensing issue as well? Like student clubs not being able to use the name “McGill” anymore, because the McGill brand must be squeaky clean. Oh, but there sure as hell can be the McGill Platinum MasterCard, and someone actually had to authorize that.

Maybe I’ll get the card and buy pornography and a kit to make GHB over the internet or something, then arrange to have it stolen so I don’t have to pay anything back. That would be squeaky clean all right!

I am an angry McGill customer!

Nicholas Touikan

PhD 4 Math
Monday, October 15th, 2007
...from letters to editor, Mcgill Daily

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Saturday, October 13, 2007

How much is a tomato worth?

Recently a column appeared in my local Vancouver Sun newspaper about the trend of eating locally grown food. The author began by describing some municipal initiatives to encourage growing local food and then arrived at the thesis of his article: "The eat-locally, grow-your-own phenomenon isn't about access to affordable food, it's about smashing the capitalist system."

At first, I thought it was some kind of joke. But the author went on to describe basic theories from Economics 101 like "comparative advantage" to show how nations that specialize in what they make most efficiently and then trade with other nations that also specialize in what they make most efficiently, end up with more stuff than if they each made those same things on their own.

His point relating to local food was that most of us don't grow our own food because it's cheaper (or maybe he means easier, since theoretically you could grow food for close to free) to buy it from someone who can do it more efficiently than you. Thus, he concludes, "Buy local campaigns are attempts to disrupt international trade."

If this sounds nuts, that's because it is. I'm sure the nice elderly lady down the street isn't thinking, "Screw the Chinese!" as she harvests fresh, tasty snap peas from her community garden, there's a bigger issue here: Our current economic system by and large completely ignores important facets of life that are worth a great deal, but have never been assigned a monetary value.

Consider this sentence from the column: "The tomato you grow yourself may seem to taste better than store-bought but it won't be cheaper." Note the word "seem", as though the tomato doesn't actually taste better, it only seems to - presumably because of the satisfaction you received from growing it. But even if that is the case, then you still enjoyed growing the tomato in the first place - and isn't that worth something? Why is it okay to put a dollar value on our labour, but not our pleasure?

And this is the problem. Only things that you can actually buy have a monetary value. So the value of a tomato is only what someone will pay for it. Not in the satisfaction of watching it grow, or the feel of the earth between your fingers when you plant it, or the warmth of the juice from the summer-ripened fruit when you bite down on it. None of these things have value because you can't buy them.

Another thing that isn't valued in our economic system is nature. More specifically, natural services like cleaning our air and water and providing a stable climate. Things grown halfway around the world and flown to our doorsteps get a lot more expensive if you actually include the cost of the damage this does to our atmosphere. So we cannot know the real price of our food unless we do full-cost accounting, which considers all of these factors that traditional economics considers "externalities." Even then, we still haven't factored in the value of community, of spending time outdoors with friends and family, and so on, that you might get from growing your own food. What are these things worth?

Needless to say, the article had me pretty depressed. Is this how people think? But then an amazing thing happened. I picked up the newspaper a couple of days later and there they were - letters. A whole page of them, in fact, from people who thought the original column was off-base, too. Each of them pointed out various flaws, but all got at the same thing: our economy is a social construct that depends on the environment and our values, not the other way around.

Reading those letters gave me hope. People get it. And more and more of them are getting it every day. Obviously, we still have a long way to go as a society, but simplistic economics that devalue some of the most important things in life are finally going the way of the dinosaur. And that's as it should be, because human life does not begin and end with a dollar sign.

By DAVID SUZUKI WITH FAISAL MOOLA
http://www.davidsuzuki.org/
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Monday, October 01, 2007

um..you did say Harvard...?

And now, just when you thought life couldn't get any better (yea right), here come news flash we're all waiting for,

Imperfect Students Wanted
Word on the street is that it's OK to stop pretending like you're perfect. According to Jess Lord, dean of admission and financial aid at Haverford College (no not Harvard, and sadly nor McGill), "everybody's imperfect. Since that's true for all (students), those that portray that aspect of themselves are that much more authentic."As colleges continue to search for unique applicants with distinguishing characteristics, some counselors say that coming across as "too perfect" only makes you sound robotic and insincere. Steven Roy Goodman, an independent college counselor, even goes as far as telling his students to make a deliberate mistake in their applications. "Sometimes it's a typo," he says. "It's pretty easy to fall into that trap of trying to do everything perfectly and there's no spark left."

uhmm... rrrrright. why don't you all try it and let me know how it turns out ;~)

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Tuesday, July 24, 2007

what the world needs more of...

...a little trip down memory lane for some sultry sizzle along with cutting edge retro animation thrown in, still, proof positive that when sparks fly and time stands still, world can be a magical place for a brief while.

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Saturday, July 14, 2007

run cody run...

Oh boy, so really we do understand no one out there wants to see a little peewee jock in action, after all greater events are happening around the world (at least in theory) , and even here at amazing McGill, we have the kick ass McGill Redmen Football team, but.. ya need to check out this 8yr old prodigy in action. He shows talent, poise, and most of all mental maturity far beyond his years. Watch for the part near the end after a field long rush touchdown where Cody calmly hands the ball back to the ref and then taps his hips to signal teammate for the twist hip airbump :) No histrionics, overblown celebrations, rubbing the goal in the opposing team's faces. Ego ridden jocks should take note. Now if only his parents are as centered as the kid...

Cody's runs

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Deascript: LOS ALAMITOS GRIFFINS, 15-0 NATIONAL CHAMPS, Cody Paul#5 highlight runs/TD's/plays from the regional championship game vs. Valencia Park and 2 Championship games from the PEE-WEE Pop Warner Super Bowl in Orlando Florida 2006

thanks Commish:))
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Monday, July 02, 2007

screw the metaphor...

Stanislavski would approve...
Bale dines on bugs

'Batman Begin's star Christian Bale prepared to eat a bowl of live maggots in new movie 'Rescue Dawn' - by dining on bugs. The actor, who is famous for going to extremes for film roles, admits he taught himself to stomach maggots by feasting on cockroaches and grasshoppers.
"I bought exotic things like grasshoppers, cockroaches and all sorts of different bugs. I had bags of them, and I was eating them like potato chips. It wasn't a huge leap to go on to maggots." Now you see why we love him. This guy doesn't just practice method acting, he turns it upside down and kicks it a mile down the road pretty much leaving Pitt,Clooney&Co. breathing dust.


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Sunday, July 01, 2007

defending the indefensible...

By the time we reach a certain age, as in old enough to drink and enter the hallowed halls of higher learning we are supposed to know the difference between right and wrong, along with a basic conceptual understanding of what is really important in life and some reasonable empathy for owning up to our mistakes regardless of consequences.
In fact the unfortunate reality is that moral decay, unabashed greed, and blatant selfishness masquerading as an individual right is the order of the day in 2007. As a collective society it seems as if we no longer aspire to amount to Anything. All we are concerned with is the comfort of our bodily wants for the present, fuck the rest. The virtually unanimous vitriolic reaction to Ann Coulter's admittedly provocative by design comments about the 'greedy' media hungry widows of 9/11 is a perfect example. If AC has one glaring fault, aside from incessant use of 'umm' during interviews(whats with that Ann), it's picking on the hapless media hounds too eager to jump on the bash-Ann-Coulter bandwagon frenzy while she laughs all the way to the bank. Here's a little piece of history, AC addressing the Johns Hopkins crowd with her typical take no prisoners attitude on racial profiling. Enough said.


Wednesday, June 20, 2007

people who should quit day job #34...

ok. so listen to this without feeling goose bumps.

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Wednesday, June 13, 2007

parenting 101...


Sunday, June 03, 2007

just what the world needs...

Hustler offers $1 million for sex smut on Congress

WASHINGTON (Reuters) - Hustler magazine is looking for some scandalous sex in Washington again -- and willing to pay for it.

"Have you had a sexual encounter with a current member of the United States Congress or a high-ranking government official?" read a full-page advertisement taken out by Larry Flynt's pornographic magazine in Sunday's Washington Post.

It offered $1 million for documented evidence of illicit intimate relations with a congressman, senator or other prominent officeholder. A toll-free number and e-mail address were provided. The last time Flynt made such an offer was in October 1998 during the drive to impeach President Bill Clinton over the Monica Lewinsky scandal.

In the following months, the pornographic publishing mogul threatened to expose one or tow members of the Republican Congress pushing for the impeachment, according to media reports at the time. That long-awaited expose, published months after Clinton's trial, dropped no bombshells, according to a 1999 Slate.com article, but Flynt's efforts played a role in the resignation of House-speaker designate Bob Livingston of Louisiana.

Flynt's target this time, if he has one, was not immediately known. No word yet on exactly when Hustler plans to make the same offer directed at the McGill University Faculty... ;~)
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Thursday, May 24, 2007

dirty little secret...

In a 2005 article in the Journal of the American Medical Association, epidemiologist John Ioannidis showed that among the 45 most highly cited clinical research findings of the past 15 years, 99 percent of molecular research had subsequently been refuted. Epidemiology findings had been contradicted in four-fifths of the cases he looked at, and the usually robust outcomes of clinical trials had a refutation rate of one in four.

The revelations struck a chord with the scientific community at large: A recent essay by Ioannidis simply entitled "Why most published research findings are false" has been downloaded more than 100,000 times; the Boston Globe called it "an instant cult classic." Now in a Möbius-strip-like twist, there is a growing body of research that is investigating, analyzing, and suggesting causes and solutions for faulty research.

Two papers published this spring in the open-access journal PLoS Medicine by Benjamin Djulbegovic from the University of South Florida and Ramal Moonesinghe from the CDC have delved into the issues raised by Ioannidis and suggested possible ways to mitigate this apparent failure of scientific enterprise. One of the suggestions is to ensure that experimental results are independently replicable. "More often than not, genuine replication is not done, and what we end up with in the literature is corroboration or indirect supporting evidence," says Moonesinghe.

The culprits appear to be the proverbial suspects: lies, damn lies, and statistics. Jonathan Sterne and George Smith, a statistician and an epidemiologist from the university of Bristol in the UK, point out in a study in British Medical Journal that "the widespread misunderstanding of statistical significance is a fundamental problem" in medical research. What's more, the scientist's bias may distort statistics. Pressure to publish can lead to "selective reporting;" the implication is that attention-seeking scientists are exaggerating their results far more often than the occasional, spectacular science fraud would suggest.

Cash-for-science practices between the nutrition and drug companies and the academics that conduct their research may also be playing a role. A survey of published results on beverages earlier this year found that research sponsored by industry is much more likely to report favorable findings than papers with other sources of funding. Although not a direct indication of bias, findings like these feed suspicion that the cherry-picking of data, hindrance of negative results, or adjustment of research is surreptitiously corrupting accuracy. In his essay, Ioannidis wrote, "The greater the financial and other interest and prejudices in a scientific field, the less likely the research findings are to be true."

Academic bias could also be to blame. As Ioannidis puts it, "Prestigious investigators may suppress via the peer-review process the appearance and dissemination of findings that refute their findings, thus condemning their field to perpetuate false dogma." Advocates of prevailing paradigms have been observed to band together in opposition against alternative ideas with perhaps more antagonism than one might expect from objective scientific debate. And the opposition isn't limited to publication of new science; jobs and grants are also more easily allocated to those affiliated with the scientific party in power.

Ioannidis is adamant that the problem is widespread. "I have heard from scientists from many different fields who think that the problems are the same in their fields as well," he says. "This is a potentially severe crisis, unless we realize the issue and try to address it."

With the debate over the causes and solutions of high rates of falsifiable research findings ongoing, how the problem is seen in the eyes of a skeptical public may be another issue altogether. Virginia Barbour, managing editor of PLoS Medicine, puts it simply: "In terms of perception, the point is that science doesn't emerge from single new findings that become 'breakthrough' stories in the media, but rather from developments that mature over months or years, with different sources of experimental validation."

by João Medeiros • Seed Magazine Posted May 21, 2007 05:14 PM



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Tuesday, May 08, 2007

say it ain't so Cate...

Skeletal Cate Blanchett is looking a bit thin on glamour

OUch.. Now quick someone bring this chick a brainwashcafe burger she looks worse than Gollum. As anyone who has seen her on screen knows, Cate Blanchett has always been slender. But the 37-year-old actress’s gaunt appearance startled onlookers as she arrived at a benefit gala. With her collarbones protruding and looking painfully thin, the Lord Of The Rings star was barely recognisable as she walked down the red carpet at the Metropolitan Museum of Art in New York.
The stick-thin look was not helped by the Oscar-winner’s shock of scarlet make-up or her swept-up hair. An observer said: "Perhaps it was just an unfortunate trick of the light, but her shoulders and chest were all bony while her collarbones looked really prominent.

"More worryingly, her hair, which had been piled up into a bun, looked thin and wispy — often a sign of dramatic weight loss." Other slender stars at the event celebrating the work of French designer Paul Poiret, who died in 1944, included Kate Moss, Lindsay Lohan and Renee Zellweger.

But the observer said: "Although Cate was apparently in good spirits, she was definitely one of the skinniest celebrities there." The actress, once a size 12, is said to be a fan of celebrity diet guru Dr Nishi Joshu. Miss Blanchett rarely speaks about her diet and lifestyle, but she was relatively quick to lose her pregnancy weight after giving birth to her sons Dashiell John, five, and three-year-old Roman.

By CLEMMIE MOODIE

Friday, May 04, 2007

speaking of truth...

Duke: 34 MBA students caught cheating

So go figure. It's not that they were cheating or that they got caught that bothers us so much, its just... well, how blatantly stupid they were in going about the process. Seriously folks, couldn't the bunch of finest minds at arguably one of the top schools in the country come up with something a little more refined? On a take home to boot. Sigh..

Duke University's Fuqua School of Business disciplined 34 first-year master of business administration students who were caught in the school's largest cheating scandal.

Fuqua investigated 38 students, marketing professor Gavan J. Fitzsimmons, who oversees the school's judicial panel, said. Four were cleared and 34 received disciplinary action ranging from expulsion to failing grades.

The allegations are the largest to hit a top US business school since 2005. Schools have been strengthening their ethics curriculums after scandals at Enron Corp. and WorldCom, which landed the firms in bankruptcy and their leaders in jail. Fuqua posts an honor code that covers cheating in every classroom.

In 2005, the Harvard Business School, Massachusetts Institute of Technology's Sloan School of Management, and others rejected 150 applicants who tapped into an online database to see whether they had been accepted.

Nine students face expulsion, and 15 face a one-year suspension and a failing grade in the course. Ten others were found guilty of lesser offenses, nine of whom received a failing grade and one who flunked the assignment, Fitzsimmons said in the e-mail.

The problem came to light when a professor noticed similarities in answers by students on a take-home test.

thanks to bloomberg news
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Sunday, April 22, 2007

beauty or truth but not both :(

"...For her beauty, as we are told, was in itself not altogether incomparable, nor such as to strike those who saw her. But converse with her had an irresistible charm, and her presence -- combined with the persuasiveness of her discourse and the character which was somehow diffused about her behaviour towards others -- had something stimulating about it."

...Sounds like a first-century version of the line "She's no babe, but she does have a nice personality".
So which average-looking lady was the Greek biographer Plutarch describing with these words? You may be surprised to learn that it was none other than the Egyptian queen Cleopatra. Plutarch's description seems a far cry from the beauty depicted in modern literature and Hollywood movies. So was Plutarch right? Or was Chaucer closer to the mark when he opined that she was "fair as is the rose in May"? Well, the recent discovery of a coin from the period may provide the definitive answer.

Antony and Cleopatra were not the handsome General and his beautiful queen Hollywood would have us believe, according to experts at Newcastle University, who have been studying the depiction of the one of history's most tragic romantic couples found on a Roman coin.

The silver coin of Mark Antony and Cleopatra was discovered in a collection from the Society of Antiquaries of Newcastle upon Tyne, which was being researched as part of the preparations for the Great North Museum, currently under development on the site of the Hancock Museum.

Antony and Cleopatra are shown on either side of the small silver coin (pictured), which is about the size of a modern five pence piece. Cleopatra is depicted with a shallow forehead, long, pointed nose, narrow lips and a sharply pointed chin, while Mark Antony has bulging eyes, a large hooked nose and a thick neck.

Clare Pickersgill, Assistant Director of Archaeological Museums at Newcastle University, said: 'The popular image we have of Cleopatra is that of a beautiful queen who was adored by Roman politicians and generals.

'The relationship between Mark Antony and Cleopatra has long been romanticised by writers, artists and film-makers. Shakespeare wrote his tragedy 'Antony and Cleopatra' in 1608, while the Orientalist artists of the nineteenth century and the modern Hollywood depictions, such as that of Elizabeth Taylor and Richard Burton in the 1963 film have added to the idea that Cleopatra was a great beauty. Recent research would seem to disagree with this portrayal, however', said Clare.

Lindsay Allason-Jones, Director of Archaeological Museums at Newcastle University, added: 'The image on the coin is far from being that of Elizabeth Taylor and Richard Burton!

'Roman writers tell us that Cleopatra was intelligent and charismatic, and that she had a seductive voice but, tellingly, they do not mention her beauty. The image of Cleopatra as a beautiful seductress is a more recent image'.

The coin is a silver denarius of Mark Antony and Cleopatra dated to 32 BC, which would have been issued by the mint of Mark Antony.

The coin itself is not enormously rare, but due to its depictions, it is very collectable. The collection has been owned by the Society of Antiquaries of Newcastle upon Tyne since the 1920s. Until now, it has been kept in a bank, but the development of the Great North Museum project (yes, that Great North project in umm...England) means that other 'hidden gems' like the Antony and Cleopatra coin, will be able to go on display to the public for the first time when the GNM opens in 2009


many thanks to University of Newcastle :))
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Saturday, April 21, 2007

power of the web...

...and we are not talking Spider Man here.

What REALLY happened at the Myspace party from hell
by NICK CRAVEN, Daily Mail
Last updated at 10:32am on 21st April 2007

Remember that advertisement for Yellow Pages from the 1990s in which a brutally hung-over young man wakes up on the sofa to recall the wild house party he threw the night before? All he had to do was let his fingers do the walking and call in a French polisher to put the damage right before his parents' return.

But 17-year-old Rachael Bell was not so fortunate. She would have needed an army to even begin to tackle the £25,000 orgy of destruction visited upon her parents' home in just a few hours.
An open invitation was placed on Rachael's MySpace page for revellers to attend a 'Skins Party' (based on a riotous episode of the controversial C4 teen drama). The invitation was headed: "Let's all trash the average, family-sized house disco party."

And they did. More than 200 young people from as far afield as London and Liverpool, converged on the £230,000 detached house in a respectable culdesac in Houghton-le-Spring and destroyed it after seven hours of drink and drug-fuelled mayhem.
As Rachael's mother Elaine, 48, so aptly put it: "The house has been raped. Every carpet's burned where they've stomped out cigarettes. They've urinated in wardrobes, pulled my clothes out and stubbed cigarettes on them. The beds have burns, food has been smeared everywhere and messages scrawled all over the walls."

Add to that the vomit-strewn clothing and condoms littering the bedrooms of Rachael's three younger siblings, stolen money and jewellery and furniture damaged beyond repair. Now, primary school teacher Mrs Bell's trust in her eldest daughter has been catastrophically shaken, as Rachael for the moment stays with a friend, too ashamed to return home. Rachael has been arrested and released on police bail as a criminal damage inquiry is under way.

Mrs Bell and her three other children are being put up in a hotel at her insurers' expense. Worse, she fears that she may not be able to return to the house at all, following its violation. Though she is separated from her husband Alan, both parents are united in their condemnation of their daughter and the teenage hoodlums she allowed in to destroy the family home.

A-level student Rachael has insisted that - despite her mother's strict instructions not to have anyone over while she looked after the house on Easter Monday - she invited only 40 or so friends. Then, she has told her mother, someone "hacked into" her MySpace page and suggested the 'Skins' theme with its invitation. From that moment on, Rachael was powerless to stop it.


Rachael, according to her account, hid in a bathroom having a "panic attack" as the uninvited mob swelled her house to breaking point.
All this would seem to exonerate Rachael as a hapless, if disobedient, victim of circumstance. But inquiries by the Mail suggest the truth may be more complex, and that Rachael's story may amount to little more than the timeworn teenager's excuse of "it wasn't me".

So what did happen before, during and after the party that so many of its attendees can barely remember, but which the residents of Chipchase Court will never forget?
Elaine Bell decided at short notice to capitalise on the glorious Bank Holiday weather by taking her three younger children to a caravan site about 15 miles away at Whitburn, a pretty coastal spot. Rachael, who ostensibly wanted to revise for her A-levels, didn't join the family group.

"I left her with firm instructions not to have any friends round while I was away," said Mrs Bell.

When and by whom the 'Skins' party invitation was added to Rachael's MySpace entry, no one can say for sure. Her version is that an innocent announcement was sent to her friends, inviting them over that night, presumably within minutes of her mother's car disappearing round the corner.
So, we are asked to believe that all of a sudden, someone else 'hacked' into her account and changed the nature of the invitation.

Just how likely is it that someone who knew Rachael had the wherewithal to obtain her password and change the entry in a matter of hours?
According to internet security sources consulted by the Mail, it's virtually impossible.

"Hacking into an account without the password is very, very difficult and time-consuming, unless you've somehow found the password out," said one expert who did not want to be named. "On the other hand, what we call 'social hacking' is far more likely, where the person has been careless with their password or has told a friend without thinking much of it."

If that were the case, would someone Rachael trusted with her password betray her so completely? If so, the list of suspects can't be very long. Mrs Bell, while still fuming at her daughter for having the party in the first place, believes her about the webspace tampering. She said: "Rachael has never done anything like this before, and there was nothing to suggest she would. She may have had the odd friend round, but that's all.

"I'm 99.9per cent sure she's telling the truth when she says that she was not responsible for what happened.
"No one knew I was going away until the Saturday, which was just two days before the party - Rachael wouldn't have had time to arrange a party on such a big scale. Someone else is behind it.
"She only planned to have a few friends round, I'm sure of that."
Naturally, Mrs Bell may want to believe her daughter, but the fact is that someone did organise the party in a short space of time. Another reason she chooses to believe her daughter is that Rachael removed all the knives in the kitchen drawer and took the television and china from the living room and put them away.
Curiously, she even taped over the clothes drawers to deter anyone from opening them. Mrs Bell draws a comforting conclusion from this: "To my mind those are not the actions of someone who was planning to let the house be smashed up."

Sceptics might wonder why, if Rachael were only expecting her 'good' friends, did she feel the need to hide the kitchen knives and tape shut the drawers?
Whatever her reasons, with those last-minute preparations made, the young hostess was by all accounts delighted to see the first revellers begin arriving in fleets of cars, taxis and minibuses shortly after 9pm.

And they just kept coming. One 17-year-old guest - who knows Rachael and definitely was invited, told the Mail he got to the house around 10pm, by which time there were around 150 people spilling out into the road. "I could hardly get in the door for people, and I soon realised a lot of them didn't know Rachael at all," said the young man, who declined to be named. "I heard people asking whose party it was.
"I noticed people stubbing tabs [cigarettes] out on the living room walls, which I thought was really disrespecting the house."
Intriguingly, despite the presence of so many unwanted guests, her friend spoke to Rachael soon after he arrived, and she was "really enjoying herself", he said.

"I wouldn't say she was off her face, but she was quite merry. I'd only been there about 20 minutes and another 20 or 30 people turned up and she didn't seem bothered.
"It was only when the police arrived in force that she started to panic."
Another party-goer, named 'Lizzie', who e-mailed a local newspaper, told a similar story (with apologies for her txtspk grammar and spelling). Her e-mail said: "we walked in threw the back door and rachael who no one knew or had met before welcomed us in and sed come in make yourselfs at home the partys already started."

A solitary police car arrived at 10pm, after neighbours realised Mrs Bell was not at home and became concerned at the large numbers of young people milling inside and outside the house. The officers asked to see the householder and an unknown teenage girl claimed there was no problem and everyone there had been invited. The police left after about five minutes. By 11pm, the party was in full swing and dozens, if not hundreds, of youngsters were drinking in the street. Outraged residents called the police again, and this time seven vehicles, including a dog van, arrived.

Police again made checks to find out who had organised the party but, according to residents the officers said they couldn't stay long. Within an hour all had gone, although one patrol car made regular passes.
Meanwhile, inside the house, partygoer 'Nicky' described the unfolding nightmare in her unique way. Her e-mail description read: "it was like a totall free for all. going threw every draw wardrobe in the house taking clothes from anywhere, a fish hook was found in the draw of rachaels brothers room and was used to carv names in the wall.

"wardrobe doors where pulled off and left on the landing for people to stamp on, door handles actully inscrewed off so people wouldnt interupt the 'yobs' having sex in everyroom in frount of all to see.
"lights in the ceiling were pulled out of the ceiling the wires snapped, the carpets were all light colours, they were black with in minuets. bed sheets where urinated on but still people slept on them, the bath was cracked off people kicking it, the toilet seemed to be dismantled, mirrors smashed, the walls were urinated on, drink was spilt up the walls on the carpets the curtains were pulled down and ripped. 'at one point, in the sitting room 4 people walked in took the radiator off the wall walked out and when we finally left in the mornin seen it dumped at the side of the road 5 minets from rachaels house."

Astonishingly, at 3am, partygoers were still arriving. Paradoxically, neighbours admitted the noise from the party itself wasn't bad. Said one: "If it hadn't been for the sheer volume of people in the street, I wouldn't have known there was a party at all."
By 8am, most revellers had left and about 20 of Rachael's friends stayed to clear up, but stopped when told by a neighbour that Mrs Bell had heard and was on her way home; Rachael and her friends fled.
At 9am, Rachael's mother arrived to find the house locked up and deserted. Opening the front door, she collapsed in tears at the state of the house she has lived in for six years, and which she had left 'immaculate' only 24 hours earlier.

This week, overseeing a massive clear-up operation by professionals, aided by a skip, she recalled the shock of that moment.
"It was devastating, just devastating," she said. "I love my house and I love it tidy and clean. I've said to Rachael she needs to give the names of those who caused the damage to the house. These people just walk off and get away with it - it's criminal.
"We'll be out of the house for a month while the specialist cleaners are in, it will need new carpets throughout."

But can the relationship with her daughter be similarly repaired? Long after the clean-up crews have done their work and departed, for Elaine Bell and her family, the emotional scars will remain.
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Wednesday, April 11, 2007

sound of silence...

Genetic wallflowers have their day.

It took all this time to finally prove what we gals (um.. some of us anyhow:) have always known, that it's the strong silent types you have to watch out for... well it turns out same applies at the genetic level. Download some vintage S&G pour yourself a cup of tea and Enjoy...

Scattered throughout the human genome are thousands of mutations that biologists have treated mostly as footnotes. They're hardly few in number—in coding regions of the genome, there are as many as 15,000—but biologists regard them as mutations that simply don't change the way a cell functions. Both in name and effect, they have been accepted as "silent." Now, however, new discoveries are showing that silent mutations appear to play an important role in dozens of human genetic diseases, a fact that is forcing biologists to discard a long-held evolutionary theory and to reexamine the very rules governing the transfer of information from DNA to proteins.
To understand the importance of this realization, it's necessary to review how information is transfered from genes to proteins. During protein synthesis the two strands of the double helix unravel, and the DNA template, composed of four nucleotide bases, is transcribed into messenger RNA (mRNA). Essentially, the information encoded in DNA is preserved in the alphabet of mRNA, which in turn is translated into amino acids, the basic building blocks of proteins. In this process, each group of three mRNA bases, called collectively a codon, signals for the addition of a particular amino acid to the growing protein. As this chain elongates, the protein spontaneously begins to fold into its final, three-dimensional conformation—a step that is essential for it to be biologically active.

A simple mutation within a gene, such as the substitution of one nucleotide for another (a "single nucleotide polymorphism," or SNP), can modify which amino acid gets incorporated into the protein, altering the way it folds and functions. Though there are an estimated 30,000 SNPs in the human genome, which account for the genetic variation among humans, most are not harmful. Biologists consider these harmless mutations "neutral" because they do not affect the fitness of an organism.

Silent mutations are a subset of SNPs. They have no impact on the amino acid sequence of proteins and, therefore, were not expected to change their function. This belief has been a central tenet of biology for decades, but new research is eroding that orthodoxy. And an article in Science this past December substantially overturned it. Dr. Chava Kimchi-Sarfaty and her colleagues at the National Institutes of Health were trying to understand why certain silent mutations occurred with unusual frequency in a gene called multidrug resistance 1 (MDR1), found in human cancer cells. MDR1 codes for a protein that sits in the membrane and pumps chemotherapy drugs out of cells, rendering the cancer cells resistant to the drugs. The team discovered that a variant of the MDR1 gene, containing certain common silent mutations, made the cells even more effective at expelling cytotoxic drugs. The question was, how?

After further investigation, the team showed that the silent mutations in MDR1 were actually slowing down the protein-making process. And since the folding of a protein into its three-dimensional shape is partially speed-dependent, these mutations were able to alter the structure—and biological function—of the protein without changing its basic building blocks. Through a series of elegant experiments, the team put to rest the idea that silent mutations were neutral.

This mechanism, which they call "translational pausing," is actually just one of several ways in which silent mutations have very recently been shown to affect protein function—and, more broadly, the fitness of an organism. It turns out that silent mutations can also change the stability of mRNA, one of the important intermediates in the transfer of information from DNA to proteins, and disrupt gene splicing, the process by which the DNA that contains genes is trimmed away from the rest of the genome.

Remarkably, it has now been shown that there are at least 40 silent mutations that cause disease in humans by changing the way a gene is spliced. One such example is CFTR, the gene that is linked to cystic fibrosis. Another example is FBN1, a gene linked to a common connective-tissue disorder called Marfan Syndrome. With this new understanding, we can now reexamine the basis of many inherited conditions for which no underlying cause has been identified.

Most fundamentally, the involvement of silent mutations in disease undermines the neutral theory of molecular evolution. This theory, posited by Motoo Kimura in the late 1960s and a powerful influence ever since, asserted that the vast majority of mutations were neutral, having no effect on the fitness of an organism, and spread through a population by chance. The fact that silent mutations are not harmless anomalies of nature means that they are not neutral. In contrast, some, if not all, silent sites must be subject to the forces of Darwinian natural selection.

—Lindsay Borthwick is a writer living in Toronto.

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Saturday, March 17, 2007

the not so dumb blondes....#13

Thursday, March 08, 2007

life in America.......??

Convicted as an ecoterrorist, a brilliant young scholar nose-dives in prison. warning: its long, but read it even if just to ask the one single question..how could this happen.

Billy Cottrell in kindergarten. When Billy Cottrell was first sent up to Lompoc Federal Penitentiary, he thought he had landed the perfect job. A brilliant student of theoretical physics at California Institute of Technology in Pasadena, Cottrell has a high-functioning form of autism that makes it difficult for him to pick up on people’s emotions, but also gives him a grave appreciation for detail. At Lompoc, he thought, he would do secretarial duty in the “boiler-room office,” spending many hours alone, filing, sorting, typing and proofreading. He could be useful.

Before his first day, however, prison officials got nervous. They knew Cottrell was smart; they’d seen his physics textbooks and writings. And wasn’t this the kid who’d been convicted of blowing up Hummers somewhere in Los Angeles? Thinking he might find a way to rig the water heaters to blow up the prison, Cottrell says, they denied him the job.

Next, Cottrell was offered a job mowing Lompoc’s copious lawn. This appealed to Cottrell’s jittery need for physical exertion. Before he was arrested, he could run a marathon in under three hours, even sleep-deprived and hopped up on Rockstar energy drink. Once again, however, the penitentiary’s guardians said no: Cottrell says prison guards worried that he might use the gasoline in the lawn mower to make a bomb.

Finally, Billy Cottrell — who got kicked out of high school a few times yet wrote an essay to the University of Chicago so impressive he was accepted into its competitive math-and-science program, who snagged an appointment at Caltech to study the arcane complexities of string theory, and who many prominent scientists consider a genius — found a job he could keep. He stood up to his knees in filth, sorting through his fellow inmates’ putrid detritus in the prison dumpsters.
Keep Reading.............

It’s a job most prisoners get as a single day’s punishment. Cottrell did it for three and a half months.

Since the day he arrived at Lompoc, 18 months ago, say his lawyers, family and friends, Cottrell has been harassed, threatened and taunted by the prison population and, in some cases, also by the guards and the administration. Because in the rigid world of prison, Cottrell has been labeled a terrorist.

Lompoc guards whispered the word at him as he passed. Visitors heard guards refer to him as their “very own ecoterrorist.” Cottrell later learned he had been used as an example in a training video on how to deal with terrorists in prison, “so now every prison guard in the country recognizes me as a terrorist on sight,” he wrote in a January 10 letter to the L.A. Weekly. He has been denied common privileges such as exercise, visitors and phone calls. Ultimately, he was banished to solitary confinement — the Hole, in prison parlance — like a violent thug.

And all because of one night in the summer of 2003, when Cottrell helped two friends deface and destroy dozens of sport utility vehicles in the name of the environment. Those who know of Cottrell and his tough prison sentence stretching to 2010 — the judge piled on an additional three years, without benefit of a jury rendering — say Cottrell is being mishandled, persecuted and, within the prison walls, compelled to become the very radical his prosecutors argued he was in court.

Meanwhile, he awaits word on two legal fronts: first, whether the California 9th Circuit believes jurors should have heard about his autism, and second, whether the federal courts will mirror the California Supreme Court in declaring judge-rendered sentence enhancements unconstitutional.

Back when he was sentenced in April 2005 to eight and a half years in prison, the judge, an ex-Marine named R. Gary Klausner, didn’t think Cottrell’s intellect or his autism should have justified leniency. But a great many scientists around the world, including Stephen Hawking, author of A Brief History of Time, have publicly objected to the apparent fact that his intellect and psychological quirks, combined with the “terrorism” label attached to his crime, have provoked prison guards to single him out.

“Billy has been selected for the especially harsh treatment reserved for ‘a terrorist,’ ” reads a letter in Cottrell’s defense signed by Hawking and seven other prominent scientists. “[His] treatment in prison, far from being rehabilitative, is nothing short of nightmarish.”

The letter was distributed to prison authorities and the U.S. 9th Circuit Court of Appeals at Cottrell’s October 18 hearing, held to determine whether the jury should have understood his psychiatric diagnosis — which the judge barred from the trial. But instead of helping him in prison, the letter seemed only to make things worse: Two weeks after the hearing, Cottrell was mysteriously thrown in the Hole.

University of Chicago professor Peter Freund, who drafted the letter his colleagues, including Hawking, later edited and signed, calls Cottrell’s ordeal “a tragedy.” One of the world’s pre-eminent authorities on theoretical physics, Freund supervised Cottrell’s senior thesis on string theory, the work that landed him a coveted spot working with Hiroshi Ooguri in Caltech’s physics department.

“If you told me John Doe was treated this way, someone I didn’t know at all, I’d feel revulsion at this systematic way the prison system is destroying a human being,” Freund says. “It’s horrible and it’s unfair. But with Billy, it’s also a loss to science. It’s too painful to watch without doing everything you can to stop it.”

There was a time, not too long ago, when Billy Cottrell was an eccentric but amiable Ph.D. candidate at Caltech, “a few degrees removed from reality,” according to Freund, but harmless. He had not yet been diagnosed with Asperger’s syndrome, the peculiar form of autism whose sufferers typically excel at advanced math and fail miserably at social skills.

But looking back, the signs were there: You might imagine him similar to Dustin Hoffman’s character in Rain Man, only less eccentric, much smarter and, as he would tell you, much better-looking. “He always talked kind of fast, like a robot,” says his mother, Heidi Schwiebert. “I used to call him my little Mr. Spock.”

Cottrell disliked silly, institutional rules: At the University of Chicago, he once refused to complete an assignment and instead turned in a lengthy and detailed essay on why the assignment was dumb. And he displayed bad judgment sometimes, says his friend Jesse Bloom, who has known him since the two were undergraduates at the University of Chicago. “When we had [David] Letterman on campus at Caltech,” Bloom remembers, “Billy ‘streaked’ [naked] across campus because people were daring him to do that.”

But he was not much of an environmentalist, or even all that liberal. In fact, in his 2004 trial, covered by Newsweek and CNN, no evidence ever emerged — and the prosecutors never suggested — that Cottrell was involved in the environmental movement at all. He watched Bill O’Reilly as regularly as he read The Nation. He voted for Schwarzenegger. He did not rebel against society so much as hold accountable the lazy people running it.

“Billy believed that most problems could be traced to lazy people who would rather complain than put in a little hard work, and he thought they should show more determination and stop making excuses,” says Bloom. “But I never saw him be mean or hostile to anyone.”

On the night of August 22, 2003, Cottrell would later testify, he had only intended to tour around Southern California with his friends Tyler Johnson and Michie Oe, plastering SUVs with bumper stickers. Going in, the plan was so innocuous, rising only to the level of a graffiti prank, that even Cottrell’s mom, Heidi, was involved.

An attractive blonde in her 50s, with big blue eyes and a curly bob haircut, Schwiebert is a horsewoman, although that’s where her interest in environmentalism ends. But she was fed up enough with polluting road hogs that she volunteered to print up bumper stickers for the three young people that would say “SUV = TERRORISM.” “I told the printer I didn’t particularly agree with the slogan myself, but I supported their right to free speech,” she recalled. At the printer’s, another “I” slipped in, and the stickers came out condemning “TERRIORISM.”

In the defense account of that night, Tyler Johnson, angry about the misspelling, demanded that Cottrell pay him back the $200 he’d spent on materials. Johnson offered to forgo the $200 if Cottrell would use his own car to chauffeur Johnson and his girlfriend, Michie Oe, around town while they spray-painted the offending gas-guzzlers.

Johnson and Oe, say Cottrell and his lawyers, had run out of gas. Cottrell agreed to take his car instead. On the way, Cottrell stopped at a gas station, and they filled several containers with gasoline.

At a Mercedes lot in Arcadia, Johnson, Cottrell and Oe sprayed seven or eight $30,000-to-$40,000 vehicles with slogans like “Fat, Lazy Americans” and “I [heart] Pollution.” In nearby Monrovia, they sprayed a Toyota Tundra and a Honda Passport with “Polluter” and “Killer.” At one car lot in Duarte, they painted 21 SUVs with the words “SUV’S Suck Hi,” and “Smog Machine.” At another Duarte lot, they hit 26 more. And on several vehicles they scrawled the initials ELF, the acronym for Earth Liberation Front.

As far as anyone knows, no ELF really exists; its Web site, www.earthliberationfront.com, is no more than a front for Viagra and repo ads (and now it’s for sale) (See LA Weekly's "Earth to ELF: Come In, Please," December 22, 2005). But in April of 2003, a few months before the SUV vandalism spree and five months before Cottrell’s arrest, the FBI’s assistant deputy director for counterterrorism, John Lewis, had gone before a Senate committee claiming that ELF and like-minded groups were America’s greatest domestic-terrorist threat. The feds were eagerly prosecuting a number of alleged environmental saboteurs who fit that view.

Because of the acronym spray-painted on the vehicles, says one of Cottrell’s lawyers, Michael Mayock. “They were watching this case at the highest levels in Washington.”

Against this tense national backdrop, Cottrell’s lawyers, Mayock and Marvin Rudnick, had asked the jury to believe that Cottrell was shocked when Johnson, without warning, stuck a rag in one of the just-filled gas containers, lit it and lobbed the homemade Molotov cocktail at a red 2003 Hummer H2 at the Clippinger Hummer dealership in West Covina. Cottrell’s defense relied on his claim that he was not part of that plan, that he insisted Johnson stop, and that he believed that Johnson would not lob another device.

But Johnson pulled out another Molotov cocktail, and then another, and another. He pummeled the Clippinger Hummer lot with so many of the minibombs, in fact, that the fires lit up 14 vehicles. All told, on that August night, after several hours of cruising, defiling and burning, 125 SUVs and other vehicles were damaged and destroyed, racking up $5 million in damage to vehicles that had traveled between states — a technicality that invoked the Interstate Commerce clause and made Cottrell’s a federal case.

The jury didn’t buy Cottrell’s defense, and no wonder. Both Johnson and Oe had disappeared before Cottrell’s arrest, and are still at large. There was no extracting their story about their night of arson. The jury had plenty of evidence to place Cottrell at the crime, including the use of his red Toyota Camry and his image on one dealership’s surveillance video.

Most important of all, Judge Klausner allowed no discussion on how Asperger’s might have affected Billy Cottrell’s judgment.

One of the most incriminating pieces of evidence left behind in Duarte that night was the carefully scrawled equation eiπ + 1 = 0, a magical formula discovered by Swiss mathematician Leonhard Euler in the 18th century. It was also the very formula Cottrell and a friend had painted on the University of Chicago’s astronomy-building tower years ago, climbing up to write it in large print near the roof. The presence of the equation on the SUVs made it easier to connect the crime to Cottrell. In effect, Cottrell had left a calling card.

It takes a certain mastery of mathematics to appreciate the beauty of this equation, known as “Euler’s identity,” a simple, elegant line of code that employs five fundamental mathematical constants. If you can’t quite grasp that — most people can’t — you might be able to understand why Cottrell seems an oddball to so many people